Inhibition of the ANT(2’’)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic a-hydroxytropolones

Nov 1

Written By Georgina Cox

2014

Georgina Cox

Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT(2”)-Ia

An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria